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After Saturdays opponent Tyrone Spong returned an doping test, oleksandr Usyk bout in the division is in jeopardy, says promoter Eddie Hearn.
Usyk, 32, gathered all of four world titles in his move and cruiserweight up a division has been highly anticipated.
But Surinamese-Dutch fighter Spongs position is in doubt following Voluntary Anti-Doping Association (Vada) testing.
Weve reserve opponents standing by, tweeted Hearn.
Weve been contacted by Vada to notify us that theres been an adverse finding in Tyrone Spongs evaluation. It has been sent to the State of Illinois commission.
Hearn said therell be an upgrade on Tuesday.
When he defended all of four world cruiserweight names usyk is scheduled to confront Spong at Chicagos Wintrust Arena within his first departure since stopping Britains Tony Bellew in November.
Spong, 34, competed before winning his first 14 battles as a fighter in kickboxing and spent a lot of his combat career.
Vada requires promoters or fighters to cover testing for the duration of a fight build-up and operates in boxing and MMA. It stated Spong was part of its testing programme in 20 September.
Even the Las Vegas-based Vada has earned a reputation in boxing and was responsible for evaluations which led to the likes of American heavyweight Jarrell Miller and also Mexicos SaulCanelo Alvarez facing bans for doping in the last several decades.
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