Robbie Henshaw will Associate Bundee Aki in Japan of the World Cup at centre in Irelands Pool A decider on Saturday.
The Irish and British Lions powerhouse has missed all three of Irelands World Cup games so far, in training after landing in Japan, having picked up a hamstring injury.
But the 26-year-old is prepared and fit to fire to some match Ireland must win with a bonus point to guarantee their place in the quarter-finals.
Ireland have rolled out the majority of their guns to have the Samoans, however Jordan Larmour has put in at full-back in place of Rob Kearney.
Tadhg Beirne replenishes his Munster colleague Peter OMahony at blindside flanker, with boss Joe Schmidt keen to ease the workload.
While Joey Carbery carries a seat on the seat, with Ireland buoyed to have back to full 26, johnny Sexton starts at fly-half .
Ireland: 15 Jordan Larmour, 14 Keith Earls, 13 Robbie Henshaw,12 Bundee Aki, 11 Jacob Stockdale, 10 Jonathan Sexton, 9 Conor Murray, 1 Cian Healy, 2 Rory Best (c), 3 Tadhg Furlong, 4 Iain Henderson, 5 James Ryan, 6 Tadhg Beirne, 7 Josh van der Flier, 8 CJ Stander
Replacements: 23 Andrew Conway, 16 Niall Scannell, 17 Dave Kilcoyne 19 Jean Kleyn 21 Luke McGrath, 22 Joey Carbery
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